SCHEMBL6448012

SCHEMBL6448012

CC(O)CN1CC(C)OC1C(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.32
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6443019 0.81 PDK1 (0.34) PDK1MAPK1KDM4EALDH1A1L3MBTL1
SCHEMBL21480029 0.79 EBP (0.33) PDK1
SCHEMBL6441562 0.78 PDK1 (0.32) PDK1
SCHEMBL6445093 0.76 PDK1 (0.32) PDK1MAPK1
SCHEMBL6444609 0.75 EBP (0.33) PDK1
SCHEMBL6441078 0.74 EBP (0.32) PDK1
SCHEMBL8421030 0.72 MAPK1 (0.47) PDK1MAPK1KDM4EALDH1A1L3MBTL1
SCHEMBL8421032 0.72 MAPK1 (0.47) PDK1MAPK1KDM4EALDH1A1L3MBTL1
SCHEMBL8421034 0.72 MAPK1 (0.47) PDK1MAPK1KDM4EALDH1A1L3MBTL1
SCHEMBL7095116 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0414962-B1 Oxazolidine compound NIPPON PAINT CO LTD (JP) 1994-03-16 EP claimed
EP-0414962-A1 Oxazolidine compound NIPPON PAINT CO., LTD. (JP) 1991-03-06 EP claimed
JP-3083990-A None JP disclosed
CN-116532109-B Preparation method of supported catalyst, obtained product and application 济南大学 2024-05-28 CN disclosed
CN-116532109-A Preparation method of supported catalyst, obtained product and application 济南大学 2023-08-04 CN disclosed
EP-1537158-B1 RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS BASF SE (DE) 2013-04-24 EP disclosed
US-20050244652-A1 Radiation curable polyurethanes with capped amino groups BASF AKTIENGESELLSCHAFT (DE) 2005-11-03 US disclosed
EP-0965604-B1 One-package thixotropic polyurethane resin composition MITSUI TAKEDA CHEMICALS INC (JP) 2002-09-04 EP disclosed
US-6255433-B1 SEALANT COMPRISING URETHANE PREPOLYMER HAVING TERMINAL FREE ISOCYANATE GROUP FORMED FROM POLYISOCYANATE, COMPOUND HAVING ACTIVE HYDROGENS, MONO-OL AND N-HYDROXYALKYL-OXAZOLIDINE, HYDROPHOBIC FINE POWDER SILICA, RING OPENING ACCELERATOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-07-03 US disclosed
EP-0965604-A1 One-package thixotropic polyurethane resin composition Takeda Chemical Industries, Ltd. (JP) 1999-12-22 EP disclosed
EP-0376293-B1 Curable composition NIPPON PAINT CO LTD (JP) 1996-03-13 EP disclosed
EP-0414962-B1 Oxazolidine compound NIPPON PAINT CO LTD (JP) 1994-03-16 EP disclosed
US-5043452-A Titanium or silicon atom containing oxazolidine compound NIPPON PAINT CO., LTD. (JP) 1991-08-27 US disclosed
US-5023298-A Blend of polymer containing carboxylic anhydride, oxazolidine compound, and alkoxysilyl groups NIPPON PAINT CO., LTD. (JP) 1991-06-11 US disclosed
JP-H0383990-A OXAZOLIDINE COMPOUND NIPPON PAINT CO LTD 1991-04-09 JP disclosed
EP-0414962-A1 Oxazolidine compound NIPPON PAINT CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0376293-A2 Curable composition NIPPON PAINT CO., LTD. (JP) 1990-07-04 EP disclosed
US-4002601-A Urethane oxazolidines BAYER AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed