⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082305 | 0.83 | TSHR (0.33) | — | |
| SCHEMBL6450963 | 0.80 | — | — | |
| SCHEMBL7178616 | 0.75 | — | — | |
| SCHEMBL2515483 | 0.74 | — | — | |
| SCHEMBL5075073 | 0.74 | NUDT1 (0.33) | — | |
| SCHEMBL6443873 | 0.74 | — | — | |
| SCHEMBL2960180 | 0.71 | CYP2C19 (0.35) | — | |
| SCHEMBL9187830 | 0.71 | — | — | |
| SCHEMBL5077731 | 0.70 | TSHR (0.35) | — | |
| SCHEMBL8573594 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565526-A | Functionalized initiators for anionic polymerization | FMC CORPORATION (US) | 1996-10-15 | — | — | US | claimed |
| US-5523447-A | REACTING LITHIUM INGOT WITH ORGANOHALIDE IN HEATED HYDROCARBON AND/OR ETHER SOLVENT; COOLING AND SEPARATING PRODUCT SOLUTION FROM LITHIUM AND LITHIUM CHLORIDE BY-PRODUCT | FMC CORPORATION (US) | 1996-06-04 | — | — | US | claimed |
| US-6858679-B2 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | FMC CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040235647-A1 | Chain extended functionalized initiators and methods of preparing and using the same | SCHWINDEMAN JAMES A (US) | 2004-11-25 | — | — | US | disclosed |
| US-6770587-B1 | Chain extended functionalized initiators and methods of preparing and using the same | FMC CORPORATION | 2004-08-03 | — | — | US | disclosed |
| EP-1028982-B1 | COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS | FMC CORP (US) | 2003-10-29 | — | — | EP | disclosed |
| US-20030153693-A1 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | QUIRK RODERIC PAUL (US) | 2003-08-14 | — | — | US | disclosed |
| US-6605564-B1 | Anionic polymerization initiators and salt additives selected from sodium chloride, sodium iodide, potassium chloride, potassium t-butoxide, for increasing the efficiency of reactions between living polymer anions and electrophiles | FMC CORPORATION | 2003-08-12 | — | — | US | disclosed |
| US-20030114611-A1 | Functionalized alkyllithium formulations with improved thermal stability and processes for making the same | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20030114592-A1 | Processes for improving stability of living polymer chain ends | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| EP-0800525-B1 | PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS | FMC CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| WO-1999025740-A1 | COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS | FMC CORPORATION (US) | 1999-05-27 | — | — | WO | disclosed |
| EP-0800525-A1 | PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS | FMC CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| EP-0800525-A4 | — | — | 1997-10-15 | — | — | EP | disclosed |
| US-5663398-A | Processes for preparing functionalized alkyllithium compounds | FMC CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5543540-A | Process for preparing trimethylsilyloxy functionalized alkyllithium | FMC CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1996003408-A1 | PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS | FMC CORPORATION (US) | 1996-02-08 | — | — | WO | disclosed |
| EP-0675140-A1 | Protected functional initiators for making terminally functionalized polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-10-04 | — | — | EP | disclosed |
| US-5416168-A | Polybutadiene, lithium catalyst and ethylene oxide terminator and hydrogenation | SHELL OIL COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5403946-A | Process of preparing trimethylsilyloxy functionalized alkyllithium compounds | FMC CORPORATION (US) | 1995-04-04 | — | — | US | disclosed |