Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455893 | 0.81 | NQO2 (0.61) | CTSSCTSKPTPN1CTSBSCN9A | |
| SCHEMBL6469664 | 0.78 | TRPV1 (0.46) | CTSSCTSKCTSBNQO2 | |
| SCHEMBL7627072 | 0.78 | CTSS (0.42) | CTSSCTSKPTPN1CTSB | |
| SCHEMBL7627063 | 0.78 | CTSS (0.42) | CTSSCTSKPTPN1CTSB | |
| SCHEMBL8662603 | 0.76 | CTSS (0.62) | CTSSCTSKPTPN1CTSBSCN9A | |
| SCHEMBL31385404 | 0.75 | PPARA (0.46) | CTSSCTSKCTSBRENACE | |
| SCHEMBL4122289 | 0.75 | CTSS (0.76) | CTSSCTSKPTPN1SCN9AACE | |
| SCHEMBL4600435 | 0.75 | CTSS (0.76) | CTSSCTSKPTPN1SCN9AACE | |
| SCHEMBL29401990 | 0.75 | CTSS (0.76) | CTSSCTSKPTPN1SCN9AACE | |
| SCHEMBL613640 | 0.75 | CTSS (0.76) | CTSSCTSKPTPN1SCN9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090011-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2005-04-06 | — | — | EP | disclosed |
| EP-1090011-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000001701-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |