SCHEMBL6448705

SCHEMBL6448705

O=c1cc[nH]n1Nc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
TDP1 Q9NUW8 4/20 0.37
ALDH1A1 P00352 8/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
ALOX12 P18054 3/20 0.36
CACNA1B Q00975 2/20 0.36
APBA1 Q02410 2/20 0.36
GAA P10253 2/20 0.36
CCR6 P51684 1/20 0.36
CASP6 P55212 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 2/20 0.32
CTSD P07339 1/20 0.32
LMNA P02545 2/20 0.32
HSP90AA1 P07900 2/20 0.32
HCRTR1 O43613 1/20 0.32
S1PR4 O95977 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8651239 0.74 MAPK11 (0.40) CYP1A2ALDH1A1MAPTHPGDCASP6
SCHEMBL4445914 0.69 CYP1A2 (0.44) CYP1A2TDP1ALDH1A1MAPTHPGD
SCHEMBL7117055 0.64 TSHR (0.53) CYP1A2ALDH1A1MAPTHPGDGAA
SCHEMBL1232067 0.64 TSHR (0.48) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL30750905 0.63 CYP1A2 (0.41) CYP1A2TDP1ALDH1A1MAPTHPGD
Phosphine SCHEMBL9466938 0.63 TSHR (0.47) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL3530061 0.63 CYP1A2 (0.45) CYP1A2TDP1ALDH1A1MAPTHPGD
SCHEMBL196531 0.61 F2 (0.54) TDP1ALDH1A1MAPTHPGDGAA
SCHEMBL18677769 0.61 CYP1A2 (0.59) CYP1A2TDP1ALDH1A1MAPTHPGD
SCHEMBL87617 0.61 CYP1A2 (0.59) CYP1A2TDP1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263876-A Hydroxyalkyl connected anilino-pyrazolone compound and synthetic method and application thereof 吉首大学 2023-12-22 CN claimed
EP-0550109-A1 Photographic silver halide and process comprising a development facilitator EASTMAN KODAK COMPANY (US) 1993-07-07 EP claimed
US-5158864-A COLOR PHOTOGRAPHIC MATERIAL AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1992-10-27 US claimed
EP-0074745-B1 PHOTOGRAPHIC CONTRAST ENHANCERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-26 EP claimed
EP-0074745-A1 Photographic contrast enhancers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-03-23 EP claimed
US-4363873-A PHENOLIC SULFONE COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-12-14 US claimed
US-4105452-A HYDROQUINONE DERIVATIVE OR PRECURSOR SUBSTITUTED WITH A HETEROCYCLIC THIO AND A ALIPHATIC OR ARYL THIO GROUP FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US claimed
JP-3189646-A None JP disclosed
JP-5249627-A None JP disclosed
CN-117263876-A Hydroxyalkyl connected anilino-pyrazolone compound and synthetic method and application thereof 吉首大学 2023-12-22 CN disclosed
CN-117263876-A Hydroxyalkyl connected anilino-pyrazolone compound and synthetic method and application thereof 吉首大学 2023-12-22 CN disclosed
CN-117263876-A Hydroxyalkyl connected anilino-pyrazolone compound and synthetic method and application thereof 吉首大学 2023-12-22 CN disclosed
US-6890707-B2 Color photographic print material AGFA-GEVAERT (BE) 2005-05-10 US disclosed
US-4105656-A PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US disclosed
US-4105452-A HYDROQUINONE DERIVATIVE OR PRECURSOR SUBSTITUTED WITH A HETEROCYCLIC THIO AND A ALIPHATIC OR ARYL THIO GROUP FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US disclosed
US-3956311-A Process for the preparation of 3-anilino-pyrazolones-(5) AGFA-GEVAERT, A.G. (DT) 1976-05-11 US disclosed
US-3956311-A Process for the preparation of 3-anilino-pyrazolones-(5) AGFA-GEVAERT, A.G. (DT) 1976-05-11 US disclosed
US-3931221-A Process for preparing 3-anilino-pyrazolones-(5) AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed
US-3931221-A Process for preparing 3-anilino-pyrazolones-(5) AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed
US-3808007-A DIFFUSION-RESISTANT PURPLE COLOR COUPLERS FOR THE PREPARATION OF PHOTOGRAPHIC COLOR PICTURES AGFA GEVAERT AG 1974-04-30 US disclosed