SCHEMBL196531

SCHEMBL196531

O=c1cc[nH]n1Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.54
PLG P00747 1/20 0.54
ELANE P08246 1/20 0.54
CTSG P08311 1/20 0.54
CMA1 P23946 1/20 0.54
CTRC Q99895 1/20 0.54
DAO P14920 1/20 0.50
EHMT2 Q96KQ7 1/20 0.46
GSK3A P49840 3/20 0.45
GSK3B P49841 3/20 0.45
MGLL Q99685 1/20 0.45
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
G6PD P11413 1/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955067 0.83 MAPT (0.54) DAOALDH1A1KMT2AMAPTHTT
SCHEMBL11394654 0.82 DAO (0.51) DAOGSK3AGSK3BMGLLMEN1
SCHEMBL11030904 0.82 IDO1 (0.44) DAOALDH1A1MEN1KMT2AMAPT
SCHEMBL9765925 0.80 TP53 (0.48) DAOALDH1A1MEN1KMT2AMAPT
SCHEMBL20504605 0.80 CHRM5 (0.39) ALDH1A1MEN1KMT2AHTTKDM4E
SCHEMBL21055329 0.76 MEN1 (0.51) F2PLGELANECTSGCMA1
SCHEMBL34463485 0.76 KDM4E (0.45) DAOALDH1A1KDM4EEP300
SCHEMBL11613138 0.76 KMT2A (0.47) DAOALDH1A1KMT2AMAPTALOX15
SCHEMBL5272693 0.72 ALDH1A1 (0.53) F2PLGELANECTSGCMA1
SCHEMBL5551879 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115919663-A Hair dyeing essential oil and preparation method thereof 广州市芊彩化妆品有限公司 2023-04-07 CN claimed
CN-115350112-A Hair dyeing composition, preparation method and application thereof, and hair dyeing mousse 广州艾柔生物科技有限公司 2022-11-18 CN claimed
CN-113143801-B Antioxidant scalp isolation muscle base solution and hair dye and preparation method thereof 泉后(广州)生物科技研究院有限公司 2022-10-04 CN claimed
US-20220242827-A1 PHENYLMETHYLPYRAZOLONE COMPOUND HAVING A NOVEL CRYSTAL FORM, AND METHOD FOR PRODUCING SAME SIA EMTEKO HOLDING (LV) 2022-08-04 US claimed
CN-114732746-A Low-irritation hair dyeing cream and preparation method thereof 广东歌秀科技有限公司 2022-07-12 CN claimed
CN-114585417-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-06-03 CN claimed
CN-114425027-A Hair dye and preparation method thereof 广州市芊彩化妆品有限公司 2022-05-03 CN claimed
CN-114423500-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-29 CN claimed
CN-114364367-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-15 CN claimed
CN-114364361-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-15 CN claimed
US-20070199159-A1 Dye-containing pellets and their use PROCTER & GAMBLE COMPANY, THE 2007-08-30 US claimed
WO-2007093954-A1 DYE-CONTAINING PELLETS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2007-08-23 WO claimed
EP-1820487-A1 Dye-containing pellets and their use Wella Aktiengesellschaft (DE) 2007-08-22 EP claimed
EP-0858796-B2 Oxidative hair dye WELLA AG (DE) 2007-04-11 EP claimed
US-20070000069-A1 Agent for colouring keratin fibres HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2007-01-04 US claimed
US-20060162097-A1 Dye-containing pellets for dyeing keratin fibres HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2006-07-27 US claimed
EP-1671619-A1 Hair colouring compositions The Procter and Gamble Company (US) 2006-06-21 EP claimed
WO-2006060570-A2 HAIR COLOURING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2006-06-08 WO claimed
US-20060117494-A1 Hair colouring compositions THE PROCTER & GAMBLE COMPANY 2006-06-08 US claimed
US-3939140-A Process for the preparation of a dyestuff consisting substantially of only unsymmetrical 1:2-chromium complex azo dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242827-A1 PHENYLMETHYLPYRAZOLONE COMPOUND HAVING A NOVEL CRYSTAL FORM, AND METHOD FOR PRODUCING SAME AGPS, AAK1, CYP4B1 F2 779/4885PLG 1810/4885ELANE 4640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.