Bicarbonate

Bicarbonate

SCHEMBL6448810

CCC(F)=C(F)F.O=C(O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.44
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28785043 0.87 FFAR3 (0.50) FFAR3TDP1ALDH1A1HDAC3HDAC1
Bicarbonate SCHEMBL1053237 0.87 FFAR3 (0.50) FFAR3TDP1ALDH1A1HDAC3HDAC1
SCHEMBL294413 0.87
Ammonia Solution, Strong SCHEMBL8532837 0.83
Bicarbonate SCHEMBL1061085 0.79 FFAR3 (0.42) FFAR3TDP1ALDH1A1HDAC3HDAC1
SCHEMBL9214685 0.77 CA2 (0.32) TDP1CA2
Tetrafluoroethylene SCHEMBL27969316 0.73 FFAR3 (0.71) FFAR3TDP1ALDH1A1HDAC3HDAC1
SCHEMBL7377951 0.73
SCHEMBL8372423 0.73
SCHEMBL3859908 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121035361-A Fluorinated electrolyte for lithium iron phosphate battery with wide temperature range and application thereof 武汉理工大学 2025-11-28 CN disclosed
CN-106159167-A Nonaqueous electrolytic solution secondary battery 丰田自动车株式会社 2016-11-23 CN disclosed
EP-1506150-A1 METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETHYLENES Bayer CropScience Aktiengesellschaft (DE) 2005-02-16 EP disclosed
WO-2003095401-A1 METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETHYLENES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-11-20 WO disclosed
WO-1998024744-A1 POLYHALOGEN HEXENES PRODUCTION THEREOF AND PRODUCTION OF HALOGENATED C4 CARBOXYLIC ACIDS FROM THESE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-11 WO disclosed