Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.57 |
| ▸ | TP53 | P04637 | 10/20 | 0.57 |
| ▸ | PKM | P14618 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | MITF | O75030 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454119 | 0.89 | SMN1; SMN2 (0.58) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL4179210 | 0.84 | GRM5 (0.64) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL4194624 | 0.84 | GRM5 (0.72) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL6454549 | 0.84 | TP53 (0.63) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL6454607 | 0.84 | GRM5 (0.62) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL4198081 | 0.83 | SMN1; SMN2 (0.68) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL13885114 | 0.82 | SMN1; SMN2 (0.57) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL4197833 | 0.81 | NPC1 (0.73) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL6454528 | 0.81 | NPC1 (0.65) | GRM5SMN1; SMN2TP53PKMRAB9A | |
| SCHEMBL22658077 | 0.80 | KDM1A (0.54) | GRM5SMN1; SMN2TP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336113-A1 | CRTH2 Receptor Ligands for Medical Use | 7TM Pharma A/S (DK) | 2011-06-22 | — | — | EP | disclosed |
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | GRM5 4040/4885SMN1; SMN2 4633/4885TP53 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.