Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 11/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458111 | 0.78 | TSHR (0.39) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL571523 | 0.76 | TSHR (0.44) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL706254 | 0.76 | TSHR (0.37) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL16497599 | 0.76 | TSHR (0.37) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL22163801 | 0.75 | TSHR (0.41) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL1101547 | 0.75 | TSHR (0.41) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL303970 | 0.74 | TSHR (0.35) | TSHRTHRBFDPSGGPS1SMPD1 | |
| Ammonia Solution, Strong SCHEMBL28224208 | 0.74 | TSHR (0.35) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL4263653 | 0.74 | TSHR (0.35) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL8470352 | 0.72 | TSHR (0.47) | TSHRTHRBFDPSGGPS1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054765-A1 | Polyorganosiloxane compositions which can be painted or coated over | GE BAYER SILICONES GMBH & CO KG (DE) | 2005-03-10 | — | — | US | disclosed |
| US-6162756-A | Tin catalysts, a process for their production, their use and cross-linkable mixtures containing them | GE BAYER SILICONES GMBH & CO. KG (DE) | 2000-12-19 | — | — | US | disclosed |