Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.40 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30381193 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL7189663 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL28571235 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL571523 | 0.97 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL1101547 | 0.97 | TSHR (0.41) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL28728010 | 0.95 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL571531 | 0.95 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6652231 | 0.89 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL19862 | 0.88 | TSHR (0.38) | TSHRTHRBFDPS | |
| SCHEMBL8663555 | 0.87 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001900-A | CURABLE COATING WITH BLOCKED ISOCYANATE OR BLOCKED ISOTHIOCYANATE AND ACTIVE HYDROGEN COMPOUND AND REACTION OF ORGANOTIN COMPOUND | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1999-12-14 | — | — | US | claimed |
| US-5714154-A | Process for the production of multiple w/o/w emulsions | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-02-03 | — | — | US | disclosed |