Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662900 | 0.97 | NR1H4 (0.42) | NR1H4CTSDELANE | |
| SCHEMBL4660631 | 0.96 | NR1H4 (0.48) | NR1H4CTSD | |
| SCHEMBL5274004 | 0.94 | NR1H4 (0.47) | NR1H4ELANE | |
| SCHEMBL4778440 | 0.92 | NR1H4 (0.38) | NR1H4 | |
| SCHEMBL5327298 | 0.92 | NR1H4 (0.45) | NR1H4CTSDELANE | |
| SCHEMBL6527603 | 0.90 | NR1H4 (0.45) | NR1H4CTSDELANE | |
| SCHEMBL4783554 | 0.89 | NR1H4 (0.43) | NR1H4CTSDELANE | |
| SCHEMBL5691316 | 0.89 | NR1H4 (0.45) | NR1H4CTSDELANE | |
| SCHEMBL4782192 | 0.89 | NR1H4 (0.42) | NR1H4CTSDELANE | |
| SCHEMBL5689551 | 0.88 | NR1H4 (0.51) | NR1H4CTSDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539120-A1 | COMBINATION OF AN IBAT INHIBITOR AND A METAL SALT FOR THE TREATMENT OF DIARRHOEA | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004006899-A1 | COMBINATION OF AN IBAT INHIBITOR AND A METAL SALT FOR THE TREATMENT OF DIARRHOEA | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | claimed |