Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | APEX1 | P27695 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223923 | 0.99 | HTT (0.74) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL9191710 | 0.96 | HTT (0.70) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL5454372 | 0.91 | HTT (0.63) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL10262308 | 0.88 | HTT (0.81) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL10262047 | 0.88 | HTT (0.81) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL15084291 | 0.88 | HTT (0.81) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL10428187 | 0.87 | HTT (1.00) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL1309117 | 0.87 | HTT (1.00) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL8682933 | 0.87 | HTT (1.00) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL10428461 | 0.87 | HTT (1.00) | HTTPOLBAPEX1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606354-B1 | POLYMERIZABLE DICHROIC AZO DYES | ROLIC AG (CH) | 2012-05-30 | — | — | EP | disclosed |
| EP-1606354-A1 | POLYMERIZABLE DICHROIC AZO DYES | Rolic AG (CH) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004085547-A1 | POLYMERIZABLE DICHROIC AZO DYES | ROLIC AG (CH) | 2004-10-07 | — | — | WO | disclosed |
| EP-1462485-A1 | Polymerizable dichroic azo dyes | Rolic AG (CH) | 2004-09-29 | — | — | EP | disclosed |