⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28177981 | 0.84 | — | — | |
| SCHEMBL27856401 | 0.81 | CHRM2 (0.32) | — | |
| SCHEMBL30688690 | 0.78 | — | — | |
| SCHEMBL5185884 | 0.76 | — | — | |
| SCHEMBL9578287 | 0.75 | CA12 (0.37) | — | |
| SCHEMBL14624754 | 0.75 | CA12 (0.37) | — | |
| SCHEMBL5011479 | 0.73 | — | — | |
| SCHEMBL14533714 | 0.70 | GPR84 (0.32) | — | |
| SCHEMBL22610216 | 0.70 | — | — | |
| SCHEMBL21443231 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702512-A | Synthesis method of cefradine | 浙江浙邦制药有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-114369102-A | Method for recovering 7-ADCA from cefradine mother liquor | 华北制药股份有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-113387824-A | High-purity D-dihydro phenyl glycine methyl ester and preparation method thereof | 华北制药股份有限公司 | 2021-09-14 | — | — | CN | claimed |
| EP-0865443-B1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | DSM NV (NL) | 2003-03-19 | — | — | EP | claimed |
| US-6503727-B1 | The invention relates to a process for the preparation of an antibiotic, in particular cefalexin, ampicillin, amoxicillin, cefaclor, cefradin, cefadroxil, cefotaxim and the like, wherein a beta-lactam core is acylated, the antibiotic is | GIST-BROCADES, B.V. (NL) | 2003-01-07 | — | — | US | claimed |
| EP-0865443-A1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | GIST-BROCADES B.V. (NL) | 1998-09-23 | — | — | EP | claimed |
| WO-1997022610-A1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | GIST-BROCADES B.V. (NL) | 1997-06-26 | — | — | WO | claimed |
| CN-113009034-B | High performance liquid analysis method of cefradine | 广东华南药业集团有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-218410545-U | D-dihydrophenyl glycine sodium salt protection drying equipment | 济南爱思医药科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-114702512-A | Synthesis method of cefradine | 浙江浙邦制药有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114369102-A | Method for recovering 7-ADCA from cefradine mother liquor | 华北制药股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-110128285-B | Preparation method of D-phenylglycine methyl ester hydrochloride/D-dihydrophenylglycine methyl ester hydrochloride | 华北制药股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113387824-A | High-purity D-dihydro phenyl glycine methyl ester and preparation method thereof | 华北制药股份有限公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-1999020786-A1 | PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC | DSM N.V. (NL) | 1999-04-29 | — | — | WO | disclosed |
| EP-0869962-A1 | PROCESS FOR THE RECOVERY OF A BETA-LACTAM ANTIBIOTIC | CHEMFERM V.O.F. (NL) | 1998-10-14 | — | — | EP | disclosed |
| EP-0865443-A1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | GIST-BROCADES B.V. (NL) | 1998-09-23 | — | — | EP | disclosed |
| EP-0815256-A1 | PROCESS FOR THE PREPARATION OF A BETA-LACTAM ANTIBIOTIC | CHEMFERM V.O.F. (NL) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997022610-A1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | GIST-BROCADES B.V. (NL) | 1997-06-26 | — | — | WO | disclosed |
| WO-1996023897-A1 | PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC | CHEMFERM V.O.F. (NL) | 1996-08-08 | — | — | WO | disclosed |
| WO-1996023797-A1 | PROCESS FOR THE RECOVERY OF A β-LACTAM ANTIBIOTIC | CHEMFERM V.O.F. (NL) | 1996-08-08 | — | — | WO | disclosed |