Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.47 |
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | HTR2C | P28335 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.47 |
| ▸ | DRD1 | P21728 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.47 |
| ▸ | HTR2B | P41595 | 5/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545857 | 0.96 | CHRM1 (0.46) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL5785290 | 0.82 | DRD2 (0.70) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL5321142 | 0.76 | DRD2 (0.70) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL14528087 | 0.72 | CHRM1 (0.47) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL4840573 | 0.71 | CHRM1 (0.48) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL4840562 | 0.71 | CHRM1 (0.48) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL4846102 | 0.70 | CHRM1 (0.44) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL4846096 | 0.70 | CHRM1 (0.44) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL4836530 | 0.70 | CHRM1 (0.46) | CHRM1DRD2HTR2CCHRM2CHRM4 | |
| SCHEMBL4836611 | 0.70 | CHRM1 (0.46) | CHRM1DRD2HTR2CCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513845-A1 | A PROCESS FOR THE PREPARATION OF OLANZAPINE AND AN INTERMEDIATE THEREFOR | Adamed SP. Z O.O. (PL) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000847-A1 | A PROCESS FOR THE PREPARATION OF OLANZAPINE AND AN INTERMEDIATE THEREFOR | ADAMED SP. Z O.O. (PL) | 2003-12-31 | — | — | WO | disclosed |