SCHEMBL6450206

SCHEMBL6450206

CCCC=CC(=O)NC(C)CCC=CC([NH])=O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.57
TAS1R1 Q7RTX1 1/20 0.57
ALDH1A1 P00352 4/20 0.34
TAAR1 Q96RJ0 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
CNR1 P21554 6/20 0.33
GAA P10253 1/20 0.33
FAAH O00519 2/20 0.32
CNR2 P34972 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4907351 0.80 TAS1R3 (0.62) TAS1R3TAS1R1ALDH1A1TAAR1CNR1
SCHEMBL4907353 0.80 TAS1R3 (0.62) TAS1R3TAS1R1ALDH1A1TAAR1CNR1
SCHEMBL1795076 0.77
SCHEMBL1795075 0.77
SCHEMBL21966701 0.74 TAS1R3 (0.44) TAS1R3TAS1R1ALDH1A1CYP1A2CYP3A4
SCHEMBL703237 0.73 TAS1R3 (1.00) TAS1R3TAS1R1ALDH1A1CNR1GAA
SCHEMBL703238 0.73 TAS1R3 (1.00) TAS1R3TAS1R1ALDH1A1CNR1GAA
SCHEMBL22044006 0.72 TAS1R3 (0.42) TAS1R3TAS1R1ALDH1A1CYP1A2CYP3A4
SCHEMBL21676457 0.69 TAS1R3 (0.41) TAS1R3TAS1R1ALDH1A1CYP1A2CYP3A4
SCHEMBL24603042 0.68 TAS1R3 (0.47) TAS1R3TAS1R1ALDH1A1TAAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP claimed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO claimed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP disclosed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO disclosed