SCHEMBL645031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2644620	0.90	GCK (0.47)	GCKEZH2SLC22A12PTGDR2FFAR4
	SCHEMBL643692	0.88	AR (0.42)	GCKEZH2SLC22A12PTGDR2LMNA
	SCHEMBL643412	0.86	MAOB (0.41)	GCKPTGDR2LMNAMAPTTSHR
	SCHEMBL643650	0.84	GCK (0.52)	GCKEZH2LMNAMAPTTSHR
	SCHEMBL2663572	0.83	GCK (0.49)	GCKLMNAMAPTTSHRRAB9A
	SCHEMBL643660	0.83	GCK (0.49)	GCKLMNAMAPTTSHRRAB9A
	SCHEMBL643703	0.83	GCK (0.53)	GCKEZH2LMNAMAPTTSHR
	SCHEMBL642273	0.82	GCK (0.48)	GCKLMNAMAPTTSHRRAB9A
	SCHEMBL644630	0.82	GCK (0.73)	GCKSLC22A12
	SCHEMBL642115	0.81	GCK (0.49)	GCKLMNAMAPTTSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.