SCHEMBL6450385

SCHEMBL6450385

OC(Cl)(Cl)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14473734 0.80
SCHEMBL9009033 0.80
SCHEMBL9851168 0.79 THRB (0.30)
SCHEMBL11836913 0.79
SCHEMBL148411 0.78
SCHEMBL24745 0.78
SCHEMBL10900687 0.76 THRB (0.31)
SCHEMBL29217140 0.76
SCHEMBL28647441 0.73
SCHEMBL6888920 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190053492-A1 SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2019-02-21 US claimed
EP-3429997-A1 N-(CYANOBENZYL)-6-(CYCLOPROPYL-CARBONYLAMINO)-4-(PHENYL)-PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES AND PLANT PROTECTION AGENTS Bayer CropScience Aktiengesellschaft (DE) 2019-01-23 EP claimed
EP-3284739-A1 SUBSTITUTED (HET) ARYL COMPOUNDS AS PESTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-02-21 EP claimed
WO-2017157885-A1 N-(CYANOBENZYL)-6-(CYCLOPROPYL-CARBONYLAMINO)-4-(PHENYL)-PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES AND PLANT PROTECTION AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 WO claimed
EP-0532918-A1 Substituted pyrazolines as pesticides BAYER AG (DE) 1993-03-24 EP claimed
US-4837364-A REACTION OF HALOBENZENE WITH TRIFLUOROETHANOL RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-06-06 US claimed
CN-118221498-A Synthesis method of fluorine compound 黑龙江迪诺医药有限公司 2024-06-21 CN disclosed
US-20190053492-A1 SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2019-02-21 US disclosed
EP-3429997-A1 N-(CYANOBENZYL)-6-(CYCLOPROPYL-CARBONYLAMINO)-4-(PHENYL)-PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES AND PLANT PROTECTION AGENTS Bayer CropScience Aktiengesellschaft (DE) 2019-01-23 EP disclosed
EP-3284739-A1 SUBSTITUTED (HET) ARYL COMPOUNDS AS PESTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-02-21 EP disclosed
WO-2017157885-A1 N-(CYANOBENZYL)-6-(CYCLOPROPYL-CARBONYLAMINO)-4-(PHENYL)-PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES AND PLANT PROTECTION AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 WO disclosed
US-6903239-B2 Fluorinated benzaldehydes BAYER CHEMICAL AKTIENGESELLSCHAFT (DE) 2005-06-07 US disclosed
US-20040171864-A1 Fluorinated aromatics LANXESS DEUTSCHLAND GMBH (DE) 2004-09-02 US disclosed
US-5525622-A PESTICIDES; INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-06-11 US disclosed
EP-0532918-A1 Substituted pyrazolines as pesticides BAYER AG (DE) 1993-03-24 EP disclosed
EP-0197868-B1 PROCESS FOR THE PREPARATION OF DICHLOROTRIFLUOROETHOXY AND ETHYLTHIOAROMATIC DERIVATIVES RHONE-POULENC CHIMIE (FR) 1988-05-18 EP disclosed
EP-0197868-B1 PROCESS FOR THE PREPARATION OF DICHLOROTRIFLUOROETHOXY AND ETHYLTHIOAROMATIC DERIVATIVES RHONE-POULENC CHIMIE (FR) 1988-05-18 EP disclosed
US-4643811-A PHOTOCHLORINATION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-02-17 US disclosed
EP-0197868-A1 Process for the preparation of dichlorotrifluoroethoxy and ethylthioaromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-10-15 EP disclosed
EP-0197868-A1 Process for the preparation of dichlorotrifluoroethoxy and ethylthioaromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-10-15 EP disclosed