Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.75 |
| ▸ | PLG | P00747 | 4/20 | 0.75 |
| ▸ | PLAU | P00749 | 1/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.57 |
| ▸ | F11 | P03951 | 13/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443939 | 0.93 | PLG (0.65) | KLKB1PLGPLAUPRSS1PRSS2 | |
| SCHEMBL7447019 | 0.92 | PLG (0.62) | KLKB1PLGPLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7266456 | 0.91 | KLKB1 (0.61) | KLKB1PLGPLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7267028 | 0.90 | KLKB1 (0.61) | KLKB1PLGPLAUPRSS1PRSS2 | |
| SCHEMBL10421058 | 0.90 | PLG (0.61) | KLKB1PLGPLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL10421061 | 0.87 | PLG (0.57) | KLKB1PLGPLAUPRSS1PRSS2 | |
| SCHEMBL10420463 | 0.85 | PLG (0.55) | KLKB1PLGPLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7442389 | 0.83 | PLG (0.53) | KLKB1PLGPLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7449011 | 0.83 | PLG (0.53) | KLKB1PLGPLAUPRSS1PRSS2 | |
| SCHEMBL5961152 | 0.82 | KLKB1 (0.74) | KLKB1PLGPLAUPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63022061-A | — | — | None | — | — | JP | disclosed |
| EP-0849256-B1 | AMIDE COMPOUNDS AND USE OF THE SAME | JAPAN TOBACCO INC (JP) | 2005-06-08 | — | — | EP | disclosed |
| EP-0849256-A1 | AMIDE COMPOUNDS AND USE OF THE SAME | Japan Tobacco Inc. (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-4895842-A | Phenylalanine derivative and proteinase inhibitor | SHOSUKE OKAMOTO (JP) | 1990-01-23 | — | — | US | disclosed |
| JP-S6322061-A | PHENYLALANINE DERIVATIVE AND PROTEASE INHIBITOR | SHOWA DENKO KK | 1988-01-29 | — | — | JP | disclosed |