Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 19/20 | 0.65 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.65 |
| ▸ | PLAU | P00749 | 2/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 16/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 16/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 16/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420463 | 0.93 | PLG (0.55) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL6450458 | 0.93 | KLKB1 (0.75) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7449011 | 0.89 | PLG (0.53) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL10421058 | 0.88 | PLG (0.61) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL7447019 | 0.88 | PLG (0.62) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7449900 | 0.87 | PLG (0.62) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL7443945 | 0.86 | PLG (0.63) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL7443929 | 0.86 | PLG (0.63) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7266456 | 0.84 | KLKB1 (0.61) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7267028 | 0.83 | KLKB1 (0.61) | PLGKLKB1PLAUPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895842-A | Phenylalanine derivative and proteinase inhibitor | SHOSUKE OKAMOTO (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0217286-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1987-04-08 | — | — | EP | disclosed |