Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.74 |
| ▸ | PLG | P00747 | 3/20 | 0.74 |
| ▸ | PLAU | P00749 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.56 |
| ▸ | F11 | P03951 | 13/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961152 | 1.00 | KLKB1 (0.74) | KLKB1PLGPLAULMNATDP1 | |
| SCHEMBL7447026 | 0.92 | PLG (0.63) | KLKB1PLGPLAULMNATDP1 | |
| SCHEMBL7447008 | 0.92 | PLG (0.63) | KLKB1PLGPLAULMNATDP1 | |
| Aminobenzoic Acid SCHEMBL7267215 | 0.92 | KLKB1 (0.62) | KLKB1PLGPLAULMNATDP1 | |
| SCHEMBL7443945 | 0.91 | PLG (0.63) | KLKB1PLGPLAUPRSS1PRSS2 | |
| SCHEMBL7443929 | 0.91 | PLG (0.63) | KLKB1PLGPLAUPRSS1PRSS2 | |
| SCHEMBL7540234 | 0.90 | PLG (0.61) | KLKB1PLGPLAULMNATDP1 | |
| SCHEMBL7540226 | 0.90 | PLG (0.61) | KLKB1PLGPLAULMNATDP1 | |
| Hydrochloric Acid SCHEMBL7268849 | 0.90 | KLKB1 (0.60) | KLKB1PLGPLAULMNATDP1 | |
| Hydrochloric Acid SCHEMBL7266461 | 0.90 | KLKB1 (0.60) | KLKB1PLGPLAULMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63022061-A | — | — | None | — | — | JP | disclosed |
| EP-0849256-B1 | AMIDE COMPOUNDS AND USE OF THE SAME | JAPAN TOBACCO INC (JP) | 2005-06-08 | — | — | EP | disclosed |
| EP-0849256-A1 | AMIDE COMPOUNDS AND USE OF THE SAME | Japan Tobacco Inc. (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-4895842-A | Phenylalanine derivative and proteinase inhibitor | SHOSUKE OKAMOTO (JP) | 1990-01-23 | — | — | US | disclosed |
| JP-S6322061-A | PHENYLALANINE DERIVATIVE AND PROTEASE INHIBITOR | SHOWA DENKO KK | 1988-01-29 | — | — | JP | disclosed |