Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 6/20 | 0.61 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.61 |
| ▸ | PLAU | P00749 | 1/20 | 0.61 |
| ▸ | F11 | P03951 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540234 | 1.00 | PLG (0.61) | PLGKLKB1PLAUF11LMNA | |
| Hydrochloric Acid SCHEMBL7275801 | 0.99 | PLG (0.60) | PLGKLKB1PLAUF11LMNA | |
| Hydrochloric Acid SCHEMBL7545755 | 0.99 | PLG (0.60) | PLGKLKB1PLAUF11LMNA | |
| SCHEMBL6450462 | 0.90 | KLKB1 (0.74) | PLGKLKB1PLAUF11LMNA | |
| SCHEMBL5961152 | 0.90 | KLKB1 (0.74) | PLGKLKB1PLAUF11LMNA | |
| SCHEMBL7440177 | 0.90 | F11 (0.60) | PLGKLKB1PLAUF11LMNA | |
| SCHEMBL7440172 | 0.90 | F11 (0.60) | PLGKLKB1PLAUF11LMNA | |
| SCHEMBL7548830 | 0.87 | PLG (0.47) | PLGKLKB1PLAUF11LMNA | |
| SCHEMBL7443945 | 0.85 | PLG (0.63) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL7443929 | 0.85 | PLG (0.63) | PLGKLKB1PLAUPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | claimed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | claimed |