Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450535 | 0.88 | ALPI (0.45) | HPGDALPIPKMPTGS1XIAP | |
| SCHEMBL18039561 | 0.79 | MME (0.43) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18039615 | 0.79 | MME (0.43) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18039657 | 0.79 | MC4R (0.43) | HPGDALDH1A1MAPT | |
| SCHEMBL18039655 | 0.79 | MC4R (0.43) | HPGDALDH1A1MAPT | |
| SCHEMBL18039558 | 0.79 | MME (0.43) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18039614 | 0.79 | MME (0.43) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL12193980 | 0.78 | NPC1 (0.47) | HPGDALPIPKMPTGS1XIAP | |
| SCHEMBL28474427 | 0.78 | NPC1 (0.47) | HPGDALPIPKMPTGS1XIAP | |
| SCHEMBL29077053 | 0.77 | SLC7A5 (0.55) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504044-A2 | CORE-SHELL POLYMERIC COMPOSITIONS | MEADWESTVACO CORPORATION, Law Department (US) | 2005-02-09 | — | — | EP | claimed |
| US-6767638-B2 | Core-shell polymeric compositions | MEADWESTVACO CORPORATION | 2004-07-27 | — | — | US | claimed |
| WO-2003097709-A2 | CORE-SHELL POLYMERIC COMPOSITIONS | MEADWESTVACO CORPORATION (US) | 2003-11-27 | — | — | WO | claimed |
| US-20030215604-A1 | Core-shell polymeric compositions | WESTVACO CORPORATION (US) | 2003-11-20 | — | — | US | claimed |
| EP-1504044-A2 | CORE-SHELL POLYMERIC COMPOSITIONS | MEADWESTVACO CORPORATION, Law Department (US) | 2005-02-09 | — | — | EP | disclosed |
| US-6767638-B2 | Core-shell polymeric compositions | MEADWESTVACO CORPORATION | 2004-07-27 | — | — | US | disclosed |
| WO-2003097709-A2 | CORE-SHELL POLYMERIC COMPOSITIONS | MEADWESTVACO CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |
| US-20030215604-A1 | Core-shell polymeric compositions | WESTVACO CORPORATION (US) | 2003-11-20 | — | — | US | disclosed |