Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 3/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18039657 | 1.00 | MC4R (0.43) | MC4RMC5RMC3RHPGDALDH1A1 | |
| SCHEMBL18039558 | 0.90 | MME (0.43) | HPGDALDH1A1MME | |
| SCHEMBL18039561 | 0.90 | MME (0.43) | HPGDALDH1A1MME | |
| SCHEMBL18039615 | 0.90 | MME (0.43) | HPGDALDH1A1MME | |
| SCHEMBL18039614 | 0.90 | MME (0.43) | HPGDALDH1A1MME | |
| SCHEMBL18039658 | 0.86 | ALDH1A1 (0.41) | MC4RMC5RMC3RALDH1A1MAPT | |
| SCHEMBL18039656 | 0.86 | ALDH1A1 (0.41) | MC4RMC5RMC3RALDH1A1MAPT | |
| SCHEMBL6450581 | 0.79 | HPGD (0.46) | HPGDALDH1A1MAPT | |
| SCHEMBL24503296 | 0.76 | SRR (0.48) | PPARGPPARAMMEACEACACB | |
| SCHEMBL30440 | 0.76 | SRR (0.48) | PPARGPPARAMMEACEACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016135751-A1 | NOVEL PROCESS FOR THE PREPARATION OF SACUBITRIL AND ITS INTERMEDIATES | MYLAN LABORATORIES LIMITED (IN) | 2016-09-01 | — | — | WO | disclosed |