Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423554 | 0.93 | CES1 (0.38) | CA1CA12CA9MMP1MMP2 | |
| SCHEMBL135639 | 0.93 | CA12 (0.42) | CA1CA12CA9MMP1MMP2 | |
| SCHEMBL28127568 | 0.93 | CA12 (0.42) | CA1CA12CA9MMP1MMP2 | |
| SCHEMBL8604788 | 0.87 | CA12 (0.37) | CA1CA12CA9MMP1MMP2 | |
| SCHEMBL6911768 | 0.87 | CA1 (0.44) | CA1CA12CA9MMP1MMP2 | |
| SCHEMBL28159724 | 0.87 | CES1 (0.39) | CA1CA12CA9CES1CES2 | |
| SCHEMBL2502247 | 0.87 | CES1 (0.39) | CA1CA12CA9CES1CES2 | |
| SCHEMBL28127574 | 0.87 | CA1 (0.44) | CA1CA12CA9MMP1MMP2 | |
| SCHEMBL6449814 | 0.86 | CA12 (0.39) | CA1CA12CA9CES1CES2 | |
| SCHEMBL7103305 | 0.86 | CA12 (0.39) | CA1CA12CA9CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509568-A1 | RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS | Lanxess Deutschland GmbH (DE) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099921-A1 | RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | WO | disclosed |
| US-20030220428-A1 | Rubber mixtures containing quaternary polymers and polar plasticizers | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-27 | — | — | US | disclosed |
| EP-0882738-B1 | DIENE RUBBER, PROCESS FOR PRODUCING THE RUBBER AND RUBBER COMPOSITION CONTAINING THE SAME | ZEON CORP (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-20020120086-A1 | Quaternary polymers with functional amine groups field of the invention | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-29 | — | — | US | disclosed |
| EP-0849321-B1 | DIENE RUBBER COMPOSITION | ZEON CORP (JP) | 2002-03-20 | — | — | EP | disclosed |
| WO-2002020632-A1 | QUATERNARY POLYMERS WITH FUNCTIONAL AMINE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | WO | disclosed |
| US-6147178-A | RUBBER COMPRISING DIENE-VINYL AROMATIC COPOLYMER BEARING QUATERNARY AMMONIUM GROUPS; TENSILE STRENGTH, WEAR RESISTANCE, HEAT RESISTANCE, IMPROVED AFFINITY FOR SILICA REINFORCEMENT | NIPPON ZEON CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-6013737-A | HAVING IMPROVED TENSILE MODULUS AND IMPROVED ABRASION RESISTANCE, COMPRISING AN AMINO GROUP-CONTAINING DIENE RUBBER OF GIVEN MOONEY VISCOSITY, AND SILICA HAVING SPECIFIC SURFACE AREA, A VULCANIZER AND VULCANIZATION ACCELERATOR | NIPPON ZEON CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0882738-A1 | DIENE RUBBER, PROCESS FOR PRODUCING THE RUBBER AND RUBBER COMPOSITION CONTAINING THE SAME | NIPPON ZEON CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0849321-A1 | DIENE RUBBER COMPOSITION | NIPPON ZEON CO., LTD. (JP) | 1998-06-24 | — | — | EP | disclosed |