SCHEMBL2502247

SCHEMBL2502247

CCCC/C(=C(/C)C(N)=O)N(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.39
LMNA P02545 1/20 0.39
CES2 O00748 5/20 0.38
ALDH1A1 P00352 2/20 0.38
CA1 P00915 3/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
TP53 P04637 2/20 0.35
FAAH O00519 3/20 0.33
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
SOAT1 P35610 1/20 0.32
KMT2A Q03164 1/20 0.32
THRB P10828 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28159724 1.00 CES1 (0.39) CES1LMNACES2ALDH1A1CA1
SCHEMBL2210988 0.88 LMNA (0.37) CES1LMNACES2ALDH1A1CA1
SCHEMBL736602 0.88 LMNA (0.37) CES1LMNACES2ALDH1A1CA1
SCHEMBL6450874 0.87 CA1 (0.42) CES1CES2ALDH1A1CA1CA12
SCHEMBL10423554 0.87 CES1 (0.38) CES1CES2ALDH1A1CA1CA12
SCHEMBL7649223 0.85 FAAH (0.32) TP53FAAHMEN1CYP1A2CYP3A4
SCHEMBL2501493 0.82 ALDH1A1 (0.48) CES1CES2ALDH1A1CA1TP53
SCHEMBL3279079 0.82 FNTA (0.46) CES1LMNACES2ALDH1A1CA1
SCHEMBL27436232 0.82 ALDH1A1 (0.48) CES1CES2ALDH1A1CA1TP53
SCHEMBL6519104 0.79 LMNA (0.34) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778654-B1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER ZEON CORP (JP) 2025-02-26 EP disclosed
US-11873364-B2 Method for producing conjugated diene rubber ZEON CORPORATION (JP) 2024-01-16 US disclosed
EP-3778654-A1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER Zeon Corporation (JP) 2021-02-17 EP disclosed
US-20210017321-A1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER ZEON CORPORATION (JP) 2021-01-21 US disclosed
EP-2772514-B1 RUBBER COMPOSITION, AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2017-08-16 EP disclosed
EP-2772515-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2017-03-01 EP disclosed
EP-2787032-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
US-9428641-B2 Rubber composition, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-08-30 US disclosed
EP-2738210-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-08-10 EP disclosed
EP-2772511-B1 RUBBER COMPOSITION, AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-06-08 EP disclosed
WO-2002020632-A1 QUATERNARY POLYMERS WITH FUNCTIONAL AMINE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 2002-03-14 WO disclosed
US-6147178-A RUBBER COMPRISING DIENE-VINYL AROMATIC COPOLYMER BEARING QUATERNARY AMMONIUM GROUPS; TENSILE STRENGTH, WEAR RESISTANCE, HEAT RESISTANCE, IMPROVED AFFINITY FOR SILICA REINFORCEMENT NIPPON ZEON CO., LTD. (JP) 2000-11-14 US disclosed
US-6013737-A HAVING IMPROVED TENSILE MODULUS AND IMPROVED ABRASION RESISTANCE, COMPRISING AN AMINO GROUP-CONTAINING DIENE RUBBER OF GIVEN MOONEY VISCOSITY, AND SILICA HAVING SPECIFIC SURFACE AREA, A VULCANIZER AND VULCANIZATION ACCELERATOR NIPPON ZEON CO., LTD. (JP) 2000-01-11 US disclosed
EP-0882738-A1 DIENE RUBBER, PROCESS FOR PRODUCING THE RUBBER AND RUBBER COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0849321-A1 DIENE RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0277580-B1 MODIFICATION OF THE WET FASTNESS OF SULPHUR DYEINGS CASSELLA Aktiengesellschaft (DE) 1993-09-01 EP disclosed
EP-0376151-B1 PROCESS FOR DYEING TEXTILE MATERIALS WITH PIGMENT DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-25 EP disclosed
US-5006129-A Dyeing textile material with pigment dyes: pre-treatment with quaternary ally ammonium salt polymer HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-09 US disclosed
EP-0376151-A2 Process for dyeing textile materials with pigment dyes HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-04 EP disclosed
US-4810254-A Wet-fastness properties of sulphur dyestuffs dyeings on cellulose treated with poly-di-allyl-ammonium salt CASSELLA AKTIENGESELLSCHAFT (DE) 1989-03-07 US disclosed