Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 15/20 | 0.81 |
| ▸ | BRAF | P15056 | 14/20 | 0.81 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.55 |
| ▸ | KIT | P10721 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 4/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1217128 | 1.00 | RAF1 (0.81) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL2891172 | 0.89 | RAF1 (1.00) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL2891760 | 0.89 | RAF1 (1.00) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL2894171 | 0.89 | RAF1 (0.79) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL2895366 | 0.89 | RAF1 (0.98) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL15049732 | 0.87 | BRAF (0.61) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL2894441 | 0.86 | RAF1 (0.91) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL3015948 | 0.84 | RAF1 (0.71) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL13618038 | 0.83 | RAF1 (0.79) | RAF1BRAFPDGFRBKITKDR | |
| SCHEMBL2891794 | 0.83 | RAF1 (0.84) | RAF1BRAFPDGFRBKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608369-A2 | USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION | CHIRON CORPORATION (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004087153-A2 | USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION | CHIRON CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |