Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.40 |
| ▸ | HRAS | P01112 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904817 | 1.00 | PDE4D (0.55) | PDE4DSLC6A2TSHRCYP2C19ADORA2A | |
| SCHEMBL10904820 | 1.00 | PDE4D (0.55) | PDE4DSLC6A2TSHRCYP2C19ADORA2A | |
| SCHEMBL10803799 | 0.91 | PDE4D (0.61) | PDE4DSLC6A2TSHRCYP2C19ADORA2A | |
| SCHEMBL10809088 | 0.91 | PDE4D (0.61) | PDE4DSLC6A2TSHRCYP2C19ADORA2A | |
| SCHEMBL16149060 | 0.87 | PDE4D (0.54) | PDE4DSLC6A2TSHRCYP2C19 | |
| SCHEMBL16149061 | 0.87 | PDE4D (0.54) | PDE4DSLC6A2TSHRCYP2C19 | |
| SCHEMBL16149062 | 0.87 | PDE4D (0.54) | PDE4DSLC6A2TSHRCYP2C19 | |
| SCHEMBL12573461 | 0.86 | PDE4D (0.53) | PDE4DSLC6A2TSHRCYP2C19ADORA2A | |
| SCHEMBL17867756 | 0.86 | PDE4D (0.53) | PDE4DSLC6A2 | |
| SCHEMBL17867755 | 0.86 | PDE4D (0.53) | PDE4DSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461046-A4 | FLUORINATED GLUCOSAMINE ANALOGS USEFUL FOR MODULATING POST-TRANSLATIONAL GLYCOSYLATIONS ON CELLS | BRIGHAM & WOMENS HOSPITAL (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1461046-A2 | FLUORINATED GLUCOSAMINE ANALOGS USEFUL FOR MODULATING POST-TRANSLATIONAL GLYCOSYLATIONS ON CELLS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2004-09-29 | — | — | EP | claimed |
| WO-2003093410-A2 | FLUORINATED GLUCOSAMINE ANALOGS USEFUL FOR MODULATING POST-TRANSLATIONAL GLYCOSYLATIONS ON CELLS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2003-11-13 | — | — | WO | claimed |