SCHEMBL6451671

SCHEMBL6451671

CC1CC[C@@H]2C[C@H](c3ccc(-c4cc(F)c(Cl)c(F)c4)cc3)CC[C@@H]2C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.34
FASN P49327 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6451678 1.00 ESR2 (0.34) ESR2FASN
SCHEMBL6453779 0.89 ESR2 (0.36) ESR2FASN
SCHEMBL6453783 0.89 ESR2 (0.36) ESR2FASN
SCHEMBL6453887 0.88 ESR2 (0.33) ESR2
SCHEMBL6453881 0.88 ESR2 (0.33) ESR2
SCHEMBL6452696 0.86 ESR2 (0.36) ESR2
SCHEMBL6452691 0.86 ESR2 (0.36) ESR2
SCHEMBL6452082 0.86 FASN (0.36) FASN
SCHEMBL6452085 0.86 FASN (0.36) FASN
SCHEMBL6459107 0.85 ESR2 (0.33) ESR2FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed