Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451730 | 1.00 | SLC18A3 (0.35) | SLC18A3LMNAMAP1LC3BHTR2AHTR2C | |
| SCHEMBL2272212 | 0.85 | SLC18A3 (0.41) | SLC18A3LMNAMAP1LC3BALDH1A1TP53 | |
| SCHEMBL2272215 | 0.85 | SLC18A3 (0.41) | SLC18A3LMNAMAP1LC3BALDH1A1TP53 | |
| SCHEMBL2272206 | 0.85 | SLC18A3 (0.41) | SLC18A3LMNAMAP1LC3BALDH1A1TP53 | |
| SCHEMBL6454181 | 0.84 | HTR3A (0.38) | SLC18A3LMNAMAP1LC3BALDH1A1TP53 | |
| SCHEMBL6458479 | 0.84 | ESR2 (0.44) | — | |
| SCHEMBL6457090 | 0.84 | KDM1A (0.34) | HTR2CHTR2B | |
| SCHEMBL6458485 | 0.84 | ESR2 (0.44) | — | |
| SCHEMBL6457093 | 0.84 | KDM1A (0.34) | HTR2CHTR2B | |
| SCHEMBL6454975 | 0.84 | KDM1A (0.34) | MAP1LC3BHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |