Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451772 | 1.00 | FASN (0.41) | FASNAPPCYP2C19KDM1ACYP3A4 | |
| SCHEMBL6460352 | 0.88 | FASN (0.41) | FASNAPPCYP2C19KDM1ACYP3A4 | |
| SCHEMBL6460347 | 0.88 | FASN (0.41) | FASNAPPCYP2C19KDM1ACYP3A4 | |
| SCHEMBL12990364 | 0.87 | FASN (0.47) | FASNAPPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL6456893 | 0.87 | FASN (0.37) | FASNAPPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL6453913 | 0.87 | GRM2 (0.41) | FASNAPPKDM1ACYP3A4CYP2C9 | |
| SCHEMBL6453917 | 0.87 | GRM2 (0.41) | FASNAPPKDM1ACYP3A4CYP2C9 | |
| SCHEMBL6456899 | 0.87 | FASN (0.37) | FASNAPPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL6455560 | 0.87 | KDM1A (0.44) | FASNKDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6455561 | 0.87 | KDM1A (0.44) | FASNKDM1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |