Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.34 |
| ▸ | MAT2A | P31153 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456893 | 1.00 | FASN (0.37) | FASNAPPMAT2ACYP3A4CYP2C9 | |
| SCHEMBL6451772 | 0.87 | FASN (0.41) | FASNAPPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6451768 | 0.87 | FASN (0.41) | FASNAPPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6456600 | 0.87 | FASN (0.35) | FASNAPPGRM2 | |
| SCHEMBL6456597 | 0.87 | FASN (0.35) | FASNAPPGRM2 | |
| SCHEMBL6455076 | 0.87 | FASN (0.34) | FASNAPP | |
| SCHEMBL6455071 | 0.87 | FASN (0.34) | FASNAPP | |
| SCHEMBL6458937 | 0.86 | MAT2A (0.35) | MAT2ALMNAALDH1A1 | |
| SCHEMBL6458931 | 0.86 | MAT2A (0.35) | MAT2ALMNAALDH1A1 | |
| SCHEMBL6454375 | 0.86 | FASN (0.34) | FASNAPPMAT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |