Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451882 | 1.00 | LMNA (0.36) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6454504 | 0.97 | MAPT (0.36) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6454501 | 0.97 | MAPT (0.36) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6456483 | 0.96 | MAPT (0.35) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6455355 | 0.96 | MAPT (0.35) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6455353 | 0.96 | MAPT (0.35) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6456489 | 0.96 | MAPT (0.35) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6457687 | 0.95 | LMNA (0.37) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6457684 | 0.95 | LMNA (0.37) | LMNAMAPTHTTHRH3CYP2D6 | |
| SCHEMBL6455501 | 0.94 | LMNA (0.34) | LMNAMAPTHTTIL2FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |