SCHEMBL6451902

SCHEMBL6451902

CCCC1CCC2CC(c3ccc(Cl)cc3)CCC2C1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.45
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
SLC6A3 Q01959 1/20 0.43
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
HTR3A P46098 1/20 0.36
LSS P48449 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6454759 1.00 DRD2 (0.45) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6451898 1.00 DRD2 (0.45) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6452414 0.96 DRD2 (0.42) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6452419 0.96 DRD2 (0.42) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL12032007 0.94 DRD2 (0.49) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL5684534 0.93 MEN1 (0.43) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL5684538 0.93 MEN1 (0.43) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6453010 0.93 CYP2C9 (0.47) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6453002 0.93 CYP2C9 (0.47) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6452974 0.92 DRD2 (0.40) DRD2CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed