Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449938 | 0.81 | AHR (0.65) | AHRCYP1A2HSD11B1SRD5A2LMNA | |
| SCHEMBL29801189 | 0.81 | AHR (0.65) | AHRCYP1A2HSD11B1SRD5A2LMNA | |
| SCHEMBL27759837 | 0.74 | AHR (0.47) | AHRCYP1A2LMNACYP2A6ALOX5 | |
| Sulfur Dioxide SCHEMBL28329775 | 0.74 | AHR (0.56) | AHRCYP1A2HSD11B1SRD5A2MAPK1 | |
| SCHEMBL4604943 | 0.74 | AHR (0.47) | AHRCYP1A2HSD11B1PTGS2 | |
| SCHEMBL2933108 | 0.72 | AHR (0.67) | AHRHSD11B1SRD5A2 | |
| SCHEMBL2473835 | 0.72 | AHR (0.54) | AHRCYP1A2LMNACYP2A6 | |
| SCHEMBL15330505 | 0.71 | AHR (0.48) | AHRMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL40603 | 0.71 | — | — | |
| SCHEMBL5544016 | 0.70 | AHR (0.57) | AHRHSD11B1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101431994-A | Use of CBx cannabinoid receptor modulators as potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | claimed |
| CN-101431998-A | Containing CBxPharmaceutical compositions of cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | claimed |
| CN-101431994-A | Use of CBx cannabinoid receptor modulators as potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | disclosed |
| CN-101431998-A | Containing CBxPharmaceutical compositions of cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | disclosed |
| CN-101426197-A | Dynamic content distributing customer terminal in TD-SCDMA mobile terminal | SHANGHAI WINGTECH ELECTRONIC T (CN) | 2009-05-06 | — | — | CN | disclosed |
| EP-1542678-A1 | 1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES AS CANNABINOID-CB sb 1 /sb RECEPTOR LIGANDS | Solvay Pharmaceuticals B.V. (NL) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004026301-A1 | 1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES AS CANNABINOID-CB1 RECEPTOR LIGANDS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2004-04-01 | — | — | WO | disclosed |