Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452094 | 1.00 | HTR1D (0.40) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6454884 | 0.99 | HTR1D (0.41) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6454878 | 0.99 | HTR1D (0.41) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6453024 | 0.98 | DRD2 (0.37) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6452898 | 0.98 | HTR1D (0.41) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6453320 | 0.98 | HTR1D (0.41) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6453317 | 0.98 | HTR1D (0.41) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6452890 | 0.98 | HTR1D (0.41) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6453027 | 0.98 | DRD2 (0.37) | HTR1DHTR1BTHRATHRBS1PR1 | |
| SCHEMBL6453761 | 0.97 | HTR1D (0.43) | HTR1DHTR1BTHRATHRBS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |