Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1481849 | 0.82 | TLR8 (0.43) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL1481852 | 0.82 | TLR8 (0.43) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL1481909 | 0.80 | POLB (0.46) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL1482178 | 0.80 | TLR8 (0.45) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL1481912 | 0.80 | POLB (0.46) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL1481444 | 0.79 | NPC1 (0.43) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL1481442 | 0.79 | NPC1 (0.43) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL1482926 | 0.76 | NPC1 (0.40) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL1482925 | 0.76 | NPC1 (0.40) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL1480335 | 0.73 | LMNA (0.40) | KDM4EMAPTLMNAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594847-A2 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Transtech Pharma, Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004071447-A2 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC. (US) | 2004-08-26 | — | — | WO | disclosed |