Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 9/20 | 0.53 |
| ▸ | CES1 | P23141 | 9/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28180792 | 0.83 | CES2 (0.53) | CES2CES1TRPM8ERN1CA1 | |
| SCHEMBL7402450 | 0.82 | CES2 (0.66) | CES2CES1TRPM8ERN1CA1 | |
| SCHEMBL7402448 | 0.82 | CES2 (0.66) | CES2CES1TRPM8ERN1CA1 | |
| SCHEMBL4068539 | 0.76 | CES2 (0.41) | CES2CES1ERN1HCAR1SRC | |
| SCHEMBL3703093 | 0.75 | CES2 (0.53) | CES2CES1CA1CA2SRC | |
| SCHEMBL27905799 | 0.75 | CES2 (0.53) | CES2CES1SRC | |
| SCHEMBL3425383 | 0.74 | CES2 (0.45) | CES2CES1TRPM8RIPK1 | |
| SCHEMBL28266437 | 0.71 | CES2 (0.53) | CES2CES1TRPM8ERN1CA1 | |
| SCHEMBL6902621 | 0.71 | SRC (0.36) | CES2CES1CA1CA2CA4 | |
| SCHEMBL27876492 | 0.71 | CES2 (0.49) | CES2CES1TRPM8ERN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562948-A2 | 6-(2-HALOGENPHENYL)-TRIAZOLOPYRIMIDINES DERIVATIVES AND THEIR USE AS FUNGICIDE | BASF Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004041824-A2 | 6-(2-HALOGENPHENYL)-TRIAZOLOPYRIMIDINES DERIVATIVES AND THEIR USE AS FUNGICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |