Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452410 | 1.00 | DRD2 (0.35) | DRD2SRD5A1LSSHTR3AL3MBTL1 | |
| SCHEMBL6452405 | 1.00 | DRD2 (0.35) | DRD2SRD5A1LSSHTR3AL3MBTL1 | |
| SCHEMBL5687117 | 0.94 | DRD2 (0.33) | DRD2SRD5A1LSSHTR3AL3MBTL1 | |
| SCHEMBL5687111 | 0.94 | DRD2 (0.33) | DRD2SRD5A1LSSHTR3AL3MBTL1 | |
| SCHEMBL6464392 | 0.87 | SLC6A2 (0.32) | SLC6A3ESR2 | |
| SCHEMBL6464394 | 0.87 | SLC6A2 (0.32) | SLC6A3ESR2 | |
| SCHEMBL6464387 | 0.87 | SLC6A2 (0.32) | SLC6A3ESR2 | |
| SCHEMBL7923289 | 0.87 | SLC6A2 (0.32) | SLC6A3ESR2 | |
| SCHEMBL6450760 | 0.85 | IDO1 (0.39) | DRD2SRD5A1HTR3AIDO1SLC2A1 | |
| SCHEMBL6450757 | 0.85 | IDO1 (0.39) | DRD2SRD5A1HTR3AIDO1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |