Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8858089 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL935698 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL6468622 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL7636894 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL28525552 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL27477590 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL28530914 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL3093909 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL7454913 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL28926190 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575284-B2 | Aluminoxane catalyst activators derived from dialkylaluminum cation precursor agents, processes for making same, and use thereof in catalysts and polymerization of olefins | ALBEMARLE CORPORATION (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130029834-A1 | Aluminoxane Catalyst Activators Derived From Dialkylalumium Cation Precursor Agents, Processes for Making Same, And Use Thereof In Catalysts And Polymerization Of Olefins | ALBEMARLE CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
| US-6884857-B1 | Olefin polymerization process using supported constrained geometry catalysts | THE DOW CHEMICAL COMPANY (US) | 2005-04-26 | — | — | US | disclosed |
| US-6858557-B1 | Supported constrained geometry olefin polymerization catalysts | THE DOW CHEMICAL COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| US-6806326-B2 | TITANIUM COMPLEXES WITH DELOCALIZED PI-BONDED CYCLOPENTADIENYL MOIETY, AND COCATALYST; FOR EXAMPLE, 1-(TERT-BUTYLAMIDO)-2-(TETRAMETHYLCYCLOPENTADIENYL)-ETHANEDIYL TITANIUM DICHLORIDE AND METHYL ALUMOXANE | THE DOW CHEMICAL COMPANY | 2004-10-19 | — | — | US | disclosed |
| US-6686488-B2 | USING COORDINATION POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY | 2004-02-03 | — | — | US | disclosed |
| US-6670432-B1 | Metal is bound to a delocalized substituted pi-bonded moiety (cyclopentadiene) to induce a constrained geometry about the metal; ethylene-styrene copolymer | THE DOW CHEMICAL COMPANY | 2003-12-30 | — | — | US | disclosed |
| US-20030065203-A1 | Constrained geometry addition polymerization catalysts | WILSON DAVID R (US) | 2003-04-03 | — | — | US | disclosed |
| EP-0764653-B1 | Polymerization catalysts, processes for their preparation, precursors therefor and methods of use | DOW CHEMICAL CO (US) | 2002-09-18 | — | — | EP | disclosed |
| US-20020128403-A1 | Constrained geometry addition polymerization catalysts | STEVENS JAMES C (US) | 2002-09-12 | — | — | US | disclosed |
| WO-2000069959-A2 | POLYMER LAYERED INORGANIC NANOCOMPOSITES | NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY (US) | 2000-11-23 | — | — | WO | disclosed |
| US-6048817-A | Polymerization of olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-11 | — | — | US | disclosed |
| US-6013819-A | AS POLYMERIZATION CATALYSTS FOR PRODUCING ADDITION POLYMERS | THE DOW CHEMICAL COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0874006-A1 | Polymerisation of olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0774468-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |
| EP-0765888-A2 | Polymers obtainable with a constrained geometry addition polymerization catalyst and process of making atactic alpha-olefin polymers with such catalysts | THE DOW CHEMICAL COMPANY (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0764654-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0764664-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0764653-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0416815-A2 | Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith | THE DOW CHEMICAL COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |