Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452588 | 1.00 | SLC6A4 (0.34) | SLC6A4DRD2GAAMAPTSLC6A2 | |
| SCHEMBL6455923 | 0.99 | GAA (0.35) | SLC6A4DRD2GAAMAPTSLC6A2 | |
| SCHEMBL6459798 | 0.99 | GAA (0.35) | SLC6A4DRD2GAAMAPTSLC6A2 | |
| SCHEMBL6459803 | 0.99 | GAA (0.35) | SLC6A4DRD2GAAMAPTSLC6A2 | |
| SCHEMBL6455919 | 0.99 | GAA (0.35) | SLC6A4DRD2GAAMAPTSLC6A2 | |
| SCHEMBL6454279 | 0.96 | SLC6A4 (0.34) | SLC6A4DRD2SLC6A2SLC6A3IDO1 | |
| SCHEMBL6454281 | 0.96 | SLC6A4 (0.34) | SLC6A4DRD2SLC6A2SLC6A3IDO1 | |
| SCHEMBL6454380 | 0.91 | CYP2C9 (0.36) | SLC6A4DRD2MAPTSLC6A2SLC6A3 | |
| SCHEMBL6454378 | 0.91 | CYP2C9 (0.36) | SLC6A4DRD2MAPTSLC6A2SLC6A3 | |
| SCHEMBL6464985 | 0.87 | DRD2 (0.42) | DRD2MAPTSLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |