Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452891 | 1.00 | PDE5A (0.34) | PDE5AESR2MAPTGAAGCGR | |
| SCHEMBL6452189 | 0.99 | GAA (0.34) | PDE5AESR2MAPTGAAGCGR | |
| SCHEMBL6452413 | 0.99 | GAA (0.34) | PDE5AESR2MAPTGAAGCGR | |
| SCHEMBL6452411 | 0.99 | GAA (0.34) | PDE5AESR2MAPTGAAGCGR | |
| SCHEMBL6452186 | 0.99 | GAA (0.34) | PDE5AESR2MAPTGAAGCGR | |
| SCHEMBL6465035 | 0.96 | ESR2 (0.36) | PDE5AESR2MAPTGAAGCGR | |
| SCHEMBL6465032 | 0.96 | ESR2 (0.36) | PDE5AESR2MAPTGAAGCGR | |
| SCHEMBL6455625 | 0.92 | CYP2C9 (0.39) | ESR2MAPTDGAT1CYP2C9ALDH1A1 | |
| SCHEMBL6455628 | 0.92 | CYP2C9 (0.39) | ESR2MAPTDGAT1CYP2C9ALDH1A1 | |
| SCHEMBL6454511 | 0.91 | MAPT (0.33) | ESR2MAPTGAASPHK1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |