Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 3/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 2/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.30 |
| ▸ | MERTK | Q12866 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465032 | 1.00 | ESR2 (0.36) | ESR2PDE5ACYP2C9GCGRRAB9A | |
| SCHEMBL6452891 | 0.96 | PDE5A (0.34) | ESR2PDE5ACYP2C9GCGRRAB9A | |
| SCHEMBL6452885 | 0.96 | PDE5A (0.34) | ESR2PDE5ACYP2C9GCGRRAB9A | |
| SCHEMBL6452189 | 0.95 | GAA (0.34) | ESR2PDE5ACYP2C9GCGRMAPT | |
| SCHEMBL6452411 | 0.95 | GAA (0.34) | ESR2PDE5ACYP2C9GCGRMAPT | |
| SCHEMBL6452186 | 0.95 | GAA (0.34) | ESR2PDE5ACYP2C9GCGRMAPT | |
| SCHEMBL6452413 | 0.95 | GAA (0.34) | ESR2PDE5ACYP2C9GCGRMAPT | |
| SCHEMBL6455625 | 0.93 | CYP2C9 (0.39) | ESR2CYP2C9MEN1MAPK1KMT2A | |
| SCHEMBL6455628 | 0.93 | CYP2C9 (0.39) | ESR2CYP2C9MEN1MAPK1KMT2A | |
| SCHEMBL6453882 | 0.91 | ESR2 (0.34) | ESR2CYP2C9RAB9AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |