Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453032 | 1.00 | ESR2 (0.34) | ESR2MGLLFPR2NAAAPDE4D | |
| SCHEMBL6461150 | 0.97 | MGLL (0.34) | ESR2MGLLFPR2NAAAPDE4D | |
| SCHEMBL6461147 | 0.97 | MGLL (0.34) | ESR2MGLLFPR2NAAAPDE4D | |
| SCHEMBL6451263 | 0.96 | MGLL (0.35) | ESR2MGLLFPR2 | |
| SCHEMBL7923263 | 0.96 | MGLL (0.35) | ESR2MGLLFPR2 | |
| SCHEMBL7923267 | 0.96 | MGLL (0.35) | ESR2MGLLFPR2 | |
| SCHEMBL6451260 | 0.96 | MGLL (0.35) | ESR2MGLLFPR2 | |
| SCHEMBL6454390 | 0.94 | CYP2C9 (0.33) | MGLLFPR2NAAAPDE4DPDE4B | |
| SCHEMBL6454386 | 0.94 | CYP2C9 (0.33) | MGLLFPR2NAAAPDE4DPDE4B | |
| SCHEMBL6453845 | 0.91 | ESR1 (0.32) | MGLLESR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |