Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918373 | 1.00 | NFE2L2 (0.61) | NFE2L2NQO2TUBB1TUBB4ATUBB | |
| SCHEMBL918107 | 0.87 | PTGS1 (0.44) | NFE2L2NQO2TUBB1TUBB4ATUBB | |
| SCHEMBL6449307 | 0.86 | TUBB1 (0.63) | NFE2L2NQO2TUBB1TUBB4ATUBB | |
| SCHEMBL918728 | 0.86 | TUBB1 (0.63) | NFE2L2NQO2TUBB1TUBB4ATUBB | |
| SCHEMBL918614 | 0.84 | NFE2L2 (0.50) | NFE2L2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6459887 | 0.84 | NFE2L2 (0.50) | NFE2L2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL917865 | 0.84 | TUBB1 (0.62) | NFE2L2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6453162 | 0.84 | TUBB1 (0.62) | NFE2L2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL919199 | 0.84 | NFE2L2 (0.64) | NFE2L2NQO2TUBB1TUBB4ATUBB | |
| SCHEMBL6453084 | 0.83 | NFE2L2 (0.60) | NFE2L2NQO2TUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | disclosed |