Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453206 | 1.00 | KCNH2 (0.37) | KCNH2ESR2HTR3ADRD2TRPV1 | |
| SCHEMBL6463483 | 0.91 | ESR2 (0.43) | ESR2HTR3ADRD2TRPV1SRD5A1 | |
| SCHEMBL6463487 | 0.91 | ESR2 (0.43) | ESR2HTR3ADRD2TRPV1SRD5A1 | |
| SCHEMBL6456390 | 0.87 | FFAR1 (0.46) | KCNH2ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456393 | 0.87 | FFAR1 (0.46) | KCNH2ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6460461 | 0.86 | ESR2 (0.40) | ESR2HTR3ADRD2TRPV1SLC6A3 | |
| SCHEMBL6460458 | 0.86 | ESR2 (0.40) | ESR2HTR3ADRD2TRPV1SLC6A3 | |
| SCHEMBL6454025 | 0.85 | ESR2 (0.37) | ESR2SLC6A2SLC6A4SLC6A3FFAR1 | |
| SCHEMBL6454022 | 0.85 | ESR2 (0.37) | ESR2SLC6A2SLC6A4SLC6A3FFAR1 | |
| SCHEMBL6460229 | 0.83 | GRM5 (0.34) | ESR2FFAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |