Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460233 | 1.00 | GRM5 (0.34) | GRM5ESR2HRH3FFAR1 | |
| SCHEMBL6456343 | 0.90 | ESR2 (0.36) | ESR2FFAR1 | |
| SCHEMBL6456347 | 0.90 | ESR2 (0.36) | ESR2FFAR1 | |
| SCHEMBL6454022 | 0.86 | ESR2 (0.37) | GRM5ESR2HRH3FFAR1 | |
| SCHEMBL6454025 | 0.86 | ESR2 (0.37) | GRM5ESR2HRH3FFAR1 | |
| SCHEMBL10527807 | 0.86 | ESR2 (0.46) | GRM5ESR2HRH3FFAR1 | |
| SCHEMBL2741540 | 0.84 | HTR2A (0.37) | ESR2HRH3 | |
| SCHEMBL6458703 | 0.84 | TRPV3 (0.32) | GRM5FFAR1 | |
| SCHEMBL6458709 | 0.84 | TRPV3 (0.32) | GRM5FFAR1 | |
| SCHEMBL6453206 | 0.83 | KCNH2 (0.37) | ESR2HRH3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |