Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453327 | 1.00 | NISCH (0.31) | NISCHNPC1RAB9AMAPTGFER | |
| SCHEMBL6452566 | 0.92 | CYP2C9 (0.31) | NISCHMAPT | |
| SCHEMBL6452560 | 0.92 | CYP2C9 (0.31) | NISCHMAPT | |
| SCHEMBL6452810 | 0.91 | TRPV3 (0.30) | — | |
| SCHEMBL6452805 | 0.91 | TRPV3 (0.30) | — | |
| SCHEMBL6456371 | 0.90 | SPHK1 (0.33) | — | |
| SCHEMBL6456368 | 0.90 | SPHK1 (0.33) | — | |
| SCHEMBL6463681 | 0.89 | SPHK1 (0.34) | MAPT | |
| SCHEMBL6463684 | 0.89 | SPHK1 (0.34) | MAPT | |
| SCHEMBL6452760 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |