Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453700 | 1.00 | FASN (0.37) | FASNCYP11B1CYP11B2APPPSEN1 | |
| SCHEMBL6457504 | 0.89 | FASN (0.39) | FASNAPPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6457509 | 0.89 | FASN (0.39) | FASNAPPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6452085 | 0.88 | FASN (0.36) | FASNAPPCYP3A4CYP2C9 | |
| SCHEMBL6464284 | 0.88 | FASN (0.40) | FASNAPPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6464288 | 0.88 | FASN (0.40) | FASNAPPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6452082 | 0.88 | FASN (0.36) | FASNAPPCYP3A4CYP2C9 | |
| SCHEMBL6453887 | 0.88 | ESR2 (0.33) | CYP11B1CYP11B2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453881 | 0.88 | ESR2 (0.33) | CYP11B1CYP11B2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453452 | 0.85 | CYP11B1 (0.36) | FASNCYP11B1CYP11B2APPPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |