SCHEMBL645401

SCHEMBL645401

COC(=O)CN(CC(=O)O)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
EYA2 O00167 1/20 0.48
APP P05067 1/20 0.48
ACE P12821 1/20 0.48
TSHR P16473 6/20 0.46
BLM P54132 2/20 0.46
PMP22 Q01453 2/20 0.46
ALOX15 P16050 2/20 0.46
CYP2C19 P33261 2/20 0.46
DRD3 P35462 2/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2A P08913 1/20 0.46
DRD1 P21728 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
ADRA1A P35348 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14719931 1.00 TDP1 (0.48) TDP1EYA2APPACETSHR
SCHEMBL20610134 0.98 TDP1 (0.46) TDP1EYA2APPACETSHR
SCHEMBL20610138 0.98 TDP1 (0.46) TDP1EYA2APPACETSHR
Benzene SCHEMBL27990648 0.95 TDP1 (0.44) TDP1EYA2APPACETSHR
SCHEMBL5852270 0.91 TDP1 (0.64) TDP1EYA2APPACETSHR
SCHEMBL5085940 0.91 TDP1 (0.64) TDP1EYA2APPACETSHR
SCHEMBL5852235 0.91 TDP1 (0.64) TDP1EYA2APPACETSHR
SCHEMBL13129733 0.91 TDP1 (0.64) TDP1EYA2APPACETSHR
Edetic Acid SCHEMBL3810362 0.91 TDP1 (0.64) TDP1EYA2APPACETSHR
SCHEMBL63502 0.89 TSHR (0.53) TSHRKDM4ELMNAHSD17B10MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240342070-A1 Topical Compositions and Formulations with Multifunctional Actions, Including Activity Against Parasites BIOSAFE TECHNOLOGIES, INC. (US) 2024-10-17 US claimed
WO-2024129458-A1 DISHWASHING DETERGENT FORMULATION ROHM AND HAAS COMPANY (US) 2024-06-20 WO claimed
EP-4384138-A1 TOPICAL COMPOSITIONS AND FORMULATIONS WITH MULTIFUNCTIONAL ACTIONS, INCLUDING ACTIVITY AGAINST PARASITES BioSafe Technologies, Inc. (US) 2024-06-19 EP claimed
US-11999925-B2 Plastic cleaning method using dispersant copolymer ROHM AND HAAS COMPANY (US) 2024-06-04 US claimed
US-11920110-B2 Automatic dishwashing composition with dispersant polymer DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-05 US claimed
WO-2024039567-A1 AUTOMATIC DISHWASHING COMPOSITION ROHM AND HAAS COMPANY (US) 2024-02-22 WO claimed
EP-3976748-B1 DISPERSANT POLYMER FOR AUTOMATIC DISHWASHING ROHM & HAAS (US) 2023-11-29 EP claimed
US-20230339824-A1 ECOLOGICAL RELEASE OF ELEMENTS AND DEGRADATION OF ORGANICS USING HETEROTROPHIC MICROORGANISMS OUT OF MULTIPLE CARRIER MATERIALS STYRIAKOVA DARINA (SK) 2023-10-26 US claimed
US-20230313073-A1 AUTOMATIC DISHWASHING FORMULATION WITH DISPERSANT COPOLYMER BLEND ROHM & HAAS (US) 2023-10-05 US claimed
EP-4214301-A1 AUTOMATIC DISHWASHING FORMULATION WITH DISPERSANT COPOLYMER BLEND Rohm and Haas Company (US) 2023-07-26 EP claimed
US-20110053819-A1 Composition RECKITT BENCKISER FINISH B.V. (NL) 2011-03-03 US claimed
US-20100323942-A1 Liquid Hand Dishwashing Detergent Composition THE PROCTER & GAMBLE COMPANY 2010-12-23 US claimed
US-20100323943-A1 Liquid Hand Dishwashing Detergent Composition THE PROCTER & GAMBLE COMPANY 2010-12-23 US claimed
WO-2010147916-A1 LIQUID HAND DISHWASHING DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2010-12-23 WO claimed
WO-2010147933-A1 LIQUID HAND DISHWASHING DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2010-12-23 WO claimed
EP-2264138-A1 Liquid hand dishwashing detergent composition The Procter & Gamble Company (US) 2010-12-22 EP claimed
EP-2264136-A1 Liquid hand dishwashing detergent composition The Procter & Gamble Company (US) 2010-12-22 EP claimed
EP-2250247-A1 COMPOSITION Reckitt Benckiser N.V. (NL) 2010-11-17 EP claimed
WO-2009095645-A1 COMPOSITION RECKITT BENCKISER N.V. (NL) 2009-08-06 WO claimed
WO-2003059314-A1 USE OF METHYL GLYCINE DIACETIC ACID OR THE DERIVATIVES THEREOF AS AN EXFOLIANT L'OREAL (FR) 2003-07-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053819-A1 Composition POLI, CPSF7, CPSF6 TDP1 304/4885EYA2 3023/4885APP 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.