Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454037 | 1.00 | HRH3 (0.38) | HRH3ACACBL3MBTL1EPHX2KDM1A | |
| SCHEMBL6454317 | 0.88 | L3MBTL1 (0.43) | HRH3L3MBTL1EPHX2KDM1ARCOR1 | |
| SCHEMBL6454321 | 0.88 | L3MBTL1 (0.43) | HRH3L3MBTL1EPHX2KDM1ARCOR1 | |
| SCHEMBL6451725 | 0.84 | KDM1A (0.38) | HRH3ACACBL3MBTL1EPHX2KDM1A | |
| SCHEMBL6451719 | 0.84 | KDM1A (0.38) | HRH3ACACBL3MBTL1EPHX2KDM1A | |
| SCHEMBL6460762 | 0.84 | APP (0.41) | KDM1A | |
| SCHEMBL6460760 | 0.84 | APP (0.41) | KDM1A | |
| SCHEMBL6454207 | 0.83 | HTR2C (0.41) | MEN1KMT2AESR2CNR1 | |
| SCHEMBL6454212 | 0.83 | HTR2C (0.41) | MEN1KMT2AESR2CNR1 | |
| SCHEMBL6454740 | 0.82 | CYP2C9 (0.38) | HRH3ACACBL3MBTL1EPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |