Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454292 | 1.00 | DRD2 (0.46) | DRD2DRD3DRD4CYP26A1CYP19A1 | |
| SCHEMBL6454787 | 0.99 | DRD2 (0.46) | DRD2DRD3DRD4CYP26A1CYP19A1 | |
| SCHEMBL6454792 | 0.99 | DRD2 (0.46) | DRD2DRD3DRD4CYP26A1CYP19A1 | |
| SCHEMBL6451654 | 0.97 | DRD2 (0.48) | DRD2DRD3DRD4CYP26A1CYP19A1 | |
| SCHEMBL6451659 | 0.97 | DRD2 (0.48) | DRD2DRD3DRD4CYP26A1CYP19A1 | |
| SCHEMBL6453464 | 0.93 | HTR1D (0.43) | DRD2DRD3S1PR1SGPL1THRA | |
| SCHEMBL6453758 | 0.93 | HTR1D (0.43) | DRD2DRD3S1PR1SGPL1THRA | |
| SCHEMBL6453468 | 0.93 | HTR1D (0.43) | DRD2DRD3S1PR1SGPL1THRA | |
| SCHEMBL6453761 | 0.93 | HTR1D (0.43) | DRD2DRD3S1PR1SGPL1THRA | |
| SCHEMBL6454904 | 0.93 | HTR1D (0.43) | DRD2DRD3S1PR1SGPL1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |